Gene IDs and their associated gene
annotations are shown on the right of the heat map. (PDF 57 KB) Additional file 2: Quality control of RNA samples by Agilent 2100 Bioanalyzer. (A) Electrophoresis files, and (B) The electropherogram of the sample well window for total RNA. The RNA Integrity Number (RIN) of all samples was > 7.0. (PDF 158 KB) Additional file 3: Oligonucleotide primers used in quantitative RT-PCR. (PDF 8 KB) References 1. Lemos JA, Burne RA: A model of efficiency: stress tolerance by streptococcus mutans. Microbiology 2008,154(Pt 11):3247–3255.PubMedCentralPubMedCrossRef 2. Lemos JA, Abranches J, Burne RA: Responses of cariogenic streptococci to environmental stresses. Current Issues Mol Biol 2005,7(1):95–107. 3. Gao XJ, Fan Y, Kent RL Jr, Van Houte J,
{Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|buy Anti-infection Compound Library|Anti-infection Compound Library ic50|Anti-infection Compound Library price|Anti-infection Compound Library cost|Anti-infection Compound Library solubility dmso|Anti-infection Compound Library purchase|Anti-infection Compound Library manufacturer|Anti-infection Compound Library research buy|Anti-infection Compound Library order|Anti-infection Compound Library mouse|Anti-infection Compound Library chemical structure|Anti-infection Compound Library mw|Anti-infection Compound Library molecular weight|Anti-infection Compound Library datasheet|Anti-infection Compound Library supplier|Anti-infection Compound Library in vitro|Anti-infection Compound Library cell line|Anti-infection Compound Library concentration|Anti-infection Compound Library nmr|Anti-infection Compound Library in vivo|Anti-infection Compound Library clinical trial|Anti-infection Compound Library cell assay|Anti-infection Compound Library screening|Anti-infection Compound Library high throughput|buy Antiinfection Compound Library|Antiinfection Compound Library ic50|Antiinfection Compound Library price|Antiinfection Compound Library cost|Antiinfection Compound Library solubility dmso|Antiinfection Compound Library purchase|Antiinfection Compound Library manufacturer|Antiinfection Compound Library research buy|Antiinfection Compound Library order|Antiinfection Compound Library chemical structure|Antiinfection Compound Library datasheet|Antiinfection Compound Library supplier|Antiinfection Compound Library in vitro|Antiinfection Compound Library cell line|Antiinfection Compound Library concentration|Antiinfection Compound Library clinical trial|Antiinfection Compound Library cell assay|Antiinfection Compound Library screening|Antiinfection Compound Library high throughput|Anti-infection Compound high throughput screening| Margolis HC: Association of caries activity with the composition of dental plaque fluid. J Dental Res 2001,80(9):1834–1839.CrossRef 4. Margolis HC, Duckworth JH, Moreno cancer metabolism inhibitor EC: Composition of pooled selleck chemical resting plaque fluid from caries-free and caries-susceptible individuals. J Dental Res 1988,67(12):1468–1475.CrossRef 5. Liu YL, Nascimento M, Burne RA: Progress toward understanding the contribution of alkali generation in dental biofilms to inhibition of dental caries. Int J Oral Sci 2012,4(3):135–140.PubMedCentralPubMedCrossRef 6. Sleator RD, Hill C: Bacterial osmoadaptation: the role of osmolytes in bacterial stress and virulence. FEMS Microbiol Rev 2002,26(1):49–71.PubMedCrossRef ADAMTS5 7. Weber A, Jung K: Profiling early osmostress-dependent gene expression in escherichia coli using DNA microarrays. J Bacteriol 2002,184(19):5502–5507.PubMedCentralPubMedCrossRef 8. Epstein W: The roles and regulation of potassium in bacteria. Prog Nucleic Acid Re 2003, 75:293–320.CrossRef 9. Ajdic D, McShan WM, McLaughlin RE, Savic G, Chang J, Carson MB, Primeaux C, Tian RY, Kenton S, Jia HG, et al.: Genome sequence of streptococcus mutans UA159, a cariogenic dental pathogen. P Natl Acad Sci USA 2002,99(22):14434–14439.CrossRef 10. Abranches J, Lemos JA, Burne RA: Osmotic stress responses of streptococcus
mutans UA159. Fems Microbiol Lett 2006,255(2):240–246.PubMedCrossRef 11. Shemesh M, Tam A, Kott-Gutkowski M, Feldman M, Steinberg D: DNA-microarrays identification of streptococcus mutans genes associated with biofilm thickness. Bmc Microbiol 2008, 8:236.PubMedCentralPubMedCrossRef 12. Shemesh M, Tam A, Aharoni R, Steinberg D: Genetic adaptation of streptococcus mutans during biofilm formation on different types of surfaces. Bmc Microbiol 2010, 10:51.PubMedCentralPubMedCrossRef 13. Ahn SJ, Wen ZT, Burne RA: Effects of oxygen on virulence traits of streptococcus mutans. J Bacteriol 2007,189(23):8519–8527.PubMedCentralPubMedCrossRef 14. Biswas I, Drake L, Erkina D, Biswas S: Involvement of sensor kinases in the stress tolerance response of streptococcus mutans. J Bacteriol 2008,190(1):68–77.