PubMedCrossRef 43. Montner P, Stark DM, Riedesel ML, Murata G, Robergs R, Timms M, Chick TW: Pre-exercise glycerol hydration improves cycling endurance time. Int J Sports Med 1996, 17:27–33.PubMedCrossRef Competing interests The authors declare that they have no competing interests. Authors’ contributions TPP assisted in the design of the study, participant recruitment, study management, data collection and analysis and was the primary author of the manuscript. TP was involved in participant recruitment, data

collection and analysis. DM assisted in study supervision and coordination and was involved in data analysis and editing the manuscript. TP and WCL were involved in participant recruitment, data collection and analysis. JRS and CH participated sample analysis and manuscript editing. YPP conceived of the study, participated in its design and coordination and helped to draft the manuscript. All authors read and Crenigacestat price approved the final manuscript.”
“Background It is commonly accepted that nutritional habits play an important role in the individual capacity of reaching optimal physical performance and this idea has been strongly underlined by the American Dietetic Association [1]. Unfortunately, a parallel nutritional information pathway is growing day

by day promoting innovative diets able, in theory, to enhance physical performances. Usually, the information provided to the public is to combine, to a defined nutritional regimen, specific supplements with the aim of reducing the length of time needed

for reaching the desired results. Nowadays, Amobarbital the culture of dietary supplementation PRN1371 is widely diffused not only among professional athletes, but also among “recreational” athletes as well as active subjects. Indeed, the global supplement use in athletes is estimated ranging between 40% and 88% [2], showing an increasing diffusion among adolescents [3]. Common supplements used with ergogenic intents include: creatine, proteins, carbohydrates, aminoacids, vitamin complex and caffeine [4]. However, beside these “traditional” supplements, a growing consumption of natural (plant-derived) products has been registered over the last years. It is estimated that more than 1400 herbs are commonly commercialized for medicinal uses worldwide and these supplements represent a GSK126 supplier multi-billion-dollar business. In the sport environment, these products are usually marketed as performance enhancing aids and they are presented as legal and free of side effects, according to the misconception that “natural” corresponds to “not harmful”. However, the publicized effects of these products and the recommended dosages are often based on little or no scientific evidence, leading the scientific community to a great concerns when considering their safety [5]. Unfortunately, the sport environment has shown an increasing interest in those “alternative natural approaches”.