g. ‘greater than the maximum value (>)’ or ‘smaller than the minimum value (<)’. However, there was categorical concordance in addition to essential agreement between AZD3965 the results obtained with the MicroScan method and the reference method for ampicillin in 19/26 isolates (73.0%), for clindamycin in 16/26 isolates (61.5%), for gentamicin in 25/26 isolates (96.2%), for imipenem in 25/26 isolates (96.2%), for levofloxacin in 26/26 isolates (100%),

for linezolid in 26/26 isolates (100%), and for vancomycin in 26/26 isolates (100%) (Table 4). MICs for some isolates differed from the reference values when determined using the MicroScan method against ampicillin (7/26 isolates, 27.0%). MICs for clindamycin determined using the MicroScan method were higher (>2 log2 dilution) compared with those obtained with the reference

CH5424802 molecular weight method for 10/26 isolates (38.5%). The Etest method showed essential agreement with the reference method for ampicillin in 16/20 isolates (80.0%), for clindamycin in 26/26 isolates (100%), for gentamicin in 26/26 isolates (100%), for imipenem in 23/23 isolates (100%), for levofloxacin in 22/22 isolates (100%), for linezolid in 26/26 isolates (100%), for meropenem in 18/23 isolates (78.3%), and for vancomycin in 23/26 isolates (88.5%) (Table 4). The Etest method showed a combination of categorical concordance and essential agreement for ampicillin in 19/26 isolates (73.0%), for clindamycin in 26/26 isolates (100%), for gentamicin in 26/26 isolates (100%), for imipenem in 26/26 isolates (100%), for levofloxacin in 26/26 isolates (100%), for linezolid in 26/26 isolates (100%), for meropenem in 21/26 isolates (80.8%), and for vancomycin in 23/26 PtdIns(3,4)P2 isolates (88.5%) (Table 4). Three isolates showed higher Etest MICs for vancomycin compared with the reference results and five showed lower MICs for meropenem. Results obtained with the MicroScan and the Etest

methods agreed with the reference results for all of the antimicrobials examined in the case of the control strain (S. aureus ATCC29213). Medical records were reviewed retrospectively to investigate the past history, the current disease, its treatment, and the outcome. In addition, medications (including antimicrobials), the dietary history, catheterization, and other procedures performed before B. cereus was isolated were reviewed (Table 1). Malignancy as an underlying disease and use of central or peripheral venous catheters during the 3-month period before B. cereus was isolated were common in both groups. Our results also showed that the use of antimicrobials for more than 3 days during the 3-month period before isolation of B. cereus was significantly larger in the BSI group (P = 0.012). This report focuses on profiles of the virulence genes and antimicrobial susceptibility of 26 B.