95 and 0.96) with the SF-36 [26]. Non-death revised grief experience inventory (NDRGEI) The Non-Death Revised Grief Experience Inventory measures

grief that is not associated with the death of a person. It is a 22-item scale measuring four domains (existential concerns, depression, tension and guilt, and physical distress) of the grief experience. Responses are scored on a 6-point scale, ranging from slight disagreement to strong agreement, with higher the total score indicating more grief and loss. The Non-Death Revised Grief Experience Inventory has a maximum score of 132. The scale has established Inhibitors,research,lifescience,medical reliability (alpha =0. 93) and validity (p=0. 001) [27]. This scale was used in a study of hope and caregivers [5]. Data collection

Inhibitors,research,lifescience,medical form Data regarding the journals (approximate daily time spent journaling, number of journal entries), and possible co-interventions such as support groups were collected using this form. Sample and setting Family caregivers in this study were defined broadly as a family member or significant other identified by the patient as his or her primary source of emotional and physical support. Rural was defined as living outside major population areas in Alberta and Saskatchewan with rural areas designated by provincial postal codes [28]. Inclusion and exclusion criteria Sample inclusion criteria were: Inhibitors,research,lifescience,medical a) female, b) 18 years of age and older, c) caring for a family member who has a diagnosis of advanced cancer and has been referred to palliative care and /or is receiving palliative care services, d) home address is a rural postal code, and e) English speaking. Exclusion criteria were a) women who were cognitively impaired as determined by the recruitment team at the site,

Inhibitors,research,lifescience,medical b) women otherwise unable to participate, in the opinion of the recruitment team and c) women caring for a family member who has a diagnosis of advanced cancer as well as dementia. Sample size Sample size was determined based on a power of 0.80, alpha of Inhibitors,research,lifescience,medical 0.05, and a moderate effect size of 0.5. Using Munro’s [29] tables for power analysis an adequate sample size would be 48. Convenience sampling was used. Thirty-six participants consented to participate. The sample was recruited using multiple strategies. Potential participants were mailed invitations to participate by the Saskatchewan and Alberta Cancer Registries. If they returned their contact information in a prepaid postage envelope, through they were contacted by a research assistant (RA) to discuss the study. In Saskatchewan, the Palliative Care Admission team in Regina Qu’Barasertib datasheet Appelle Health Region and nurses at the Saskatchewan Cancer Agency also identified potential participants. In Alberta, the Alberta Health Services Cancer Care and Community Cancer Clinics in rural communities also identified potential participants. Those who agreed were contacted by trained RAs (experienced Registered Nurses) to arrange a time to meet to discuss the study.